Acinetobacter baumannii in suspected bacterial infections: Association between multidrug resistance, virulence genes, & amp; biofilm production

CONCLUSIONS: The majority of isolates studied were from lower respiratory tract specimens. The high MDR rate and its positive association with biofilm formation indicate the nosocomial distribution of A. baumannii. The biofilm formation and the presence of Bap were not interrelated, indicating that biofilm formation was not regulated by a single factor. The MDR rate and the presence of OmpA and Bap showed a positive association (P<0.05). The isolates co-harbouring different carbapenem resistance genes were the predominant biofilm producers, which will seriously limit the therapeutic options suggesting the need for strict antimicrobial stewardship and molecular surveillance in hospitals.PMID:38006347 | DOI:10.4103/ijmr.ijmr_3470_21

Source: Indian J Med Res - November 25, 2023 Category: Research Authors: Deepan Gautam Karma Gurmey Dolma Bidita Khandelwal Ramesh Kumar Goyal Watcharapong Mitsuwan Maria de Lourdes Gomes Pereira Wiyada Kwanhian Klangbud Madhu Gupta Polrat Wilairatana Abolghasem Siyadatpanah Christophe Wiart Veeranoot Nissapatorn Source Type: research