Canagliflozin ameliorates high glucose-induced apoptosis in NRK-52E cells via inhibiting oxidative stress and activating AMPK/mTOR-mediated autophagy

CONCLUSION: Canagliflozin effectively ameliorate HG-induced apoptosis of NRK-52E cells in vitro that involved its antioxidant effect and induction of autophagy through the AMPK/mTOR pathway.PMID:37976004 | DOI:10.1007/s11033-023-08855-x

Source: Molecular Biology Reports - November 17, 2023 Category: Molecular Biology Authors: Hong Liu Weidong Chen Sheng Wan Ye Chen Mengjing Fu Zengsi Wang Fei Xiong Yanmin Zhang Source Type: research