Pan-cancer Analysis Combined with Experiments Deciphers PHB Regulation for Breast Cancer Cell Survival and Predicts Biomarker Function

CONCLUSION: Although prohibitin is over-expressed in various cancer types, it functions as an important tumor suppressor that may suppress breast cancer cell proliferation and the invasive ability of MCF-7 by influencing its DNA synthesis and promoting cell apoptosis. All these may be likely associated with P53, erbB-2, and Bcl-2.PMID:37957856 | DOI:10.2174/0113862073266248231024113533
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Source Type: research