Cholestenoic Acid as Endogenous Epigenetic Regulator Decreases Hepatocyte Lipid Accumulation in Vitro and in Vivo

This study shows that CA as an endogenous epigenetic regulator decreases lipid accumulation via epigenetic regulation. The results indicate that CA can be considered a potential therapeutic target for the treatment of metabolic disorders.PMID:37961761 | DOI:10.1152/ajpgi.00184.2023

Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - November 14, 2023 Category: Physiology Authors: Yaping Wang William M Pandak Phillip B Hylemon Hae-Ki Min John Min Michael Fuchs Arun J Sanyal Shunlin Ren Source Type: research