Hyperthermia elevates brain temperature and improves behavioural signs in animal models of autism spectrum disorder

ConclusionsThe data are the first, to our knowledge, to demonstrate that elevated body temperature can improve behavioural signs in 2 distinct ASD models. Given the developmental nature of ASD, evidence that symptoms may be improved by environmental perturbations indicates possibilities for improving function in these individuals. Since experimental hyperthermia in patients would carry significant risks, it is now essential to pursue molecular mechanisms through which hyperthermia might bring about the observed benefits.
Source: Molecular Autism - Category: Molecular Biology Source Type: research