Risk of secondary progressive multiple sclerosis after early worsening of disability

Conclusions Early disability increase during RRMS is associated with a greater risk of SPMS but not the rate of disability progression during SPMS. The deterioration associated with early relapses represents a potentially treatable risk factor of SPMS. Trial registration number Australian New Zealand Clinical Trials Registry (ACTRN12605000455662).

http://jnnp.bmj.com/cgi/content/short/94/12/984?rss=1

Source: Journal of Neurology, Neurosurgery and Psychiatry - November 15, 2023 Category: Neurosurgery Authors: Dzau, W., Sharmin, S., Patti, F., Izquierdo, G., Eichau, S., Prat, A., Girard, M., Duquette, P., Onofrj, M., Lugaresi, A., Ozakbas, S., Gerlach, O., Boz, C., Grammond, P., Terzi, M., Amato, M. P., La Spitaleri, D., Ramo-Tello, C., Maimone, D., Cartechini, Tags: Multiple sclerosis Source Type: research