Major immunophenotypic abnormalities in patients with primary adrenal insufficiency of different etiology

DiscussionIn patients with different etiologies of PAI, distinct differences in T and NK cell-phenotypes became apparent despite the use of same GC preparation and dose. Our results highlight unsuspected differences in immune cell composition and function in PAI patients of different causes and suggest disease-specific alterations that might necessitate disease-specific treatment.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research