Evaluation of the effects of storage conditions on spray-dried siRNA-LNPs before and after subsequent drying

This study confirms the stability of spray-dried and subsequently dried LNPs over at least 90 days at 4 °C and 25 °C emphasizing the potential of dry powder inhalation of RNA-loaded LNPs as a therapy option for pulmonary diseases.PMID:37956785 | DOI:10.1016/j.ejpb.2023.11.007
Source: European Journal of Pharmaceutics and Biopharmaceutics - Category: Drugs & Pharmacology Authors: Source Type: research