Interactive neuroinflammation pathways and transcriptomics-based identification of drugs and chemical compounds for schizophrenia

Conclusions: New neuroinflammatory pathways incorporating the extracellular matrix, glutamatergic neurons, and astrocytes in the aetiology of schizophrenia were established. Transcriptomics based network analysis provided novel targets, including extra-synaptic glutamate receptors, glutamate transporters and extracellular matrix molecules that can be evaluated for therapeutic strategies.PMID:37961844 | DOI:10.1080/15622975.2023.2281514
Source: The World Journal of Biological Psychiatry - Category: Psychiatry Authors: Source Type: research