HLA class I allele loss and bone marrow transplantation outcomes in immune aplastic anemia

Immune aplastic anemia (AA) is T-cell-mediated bone marrow failure,1 which can be managed through hematopoietic stem cell transplantation (HSCT) or immunosuppressive therapy (IST) based on patient age and availability of an appropriate donor.2,3

Source: Biology of Blood and Marrow Transplantation - November 13, 2023 Category: Hematology Authors: Yoshitaka Zaimoku, Takamasa Katagiri, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki, Toshihiro Miyamoto, Shinji Nakao Source Type: research