Disruption of hypoxia inducible factor-2 α in neutrophils decreases colitis-associated colon cancer

In conclusion, we found that the loss of neutrophil-specific HIF-2α slows colon tumor growth and progression by reducing the levels of inflammatory mediators.PMID:37933447 | DOI:10.1152/ajpgi.00182.2023

Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - November 7, 2023 Category: Physiology Authors: Rashi Singhal Nikhil Kumar Kotla Sumeet Solanki Wesley Huang Hannah N Bell Marwa O Elderany Cristina Castillo Yatrik M Shah Source Type: research