83. Cytogenetic and molecular characterization of IDH-mutant adult-type diffuse gliomas with near-total 1p/19q co-deletions
Whole-arm 1p/19q co-deletion is a diagnostic criterion for oligodendroglioma, IDH-mutant and 1p/19q-codeleted. The significance of near-total co-deletions of 1p and 19q arms (( ≥75%) is unclear. We cytogenetically and molecularly characterized 15 IDH-mutant adult-type diffuse gliomas with near-total 1p/19q co-deletions encountered in routine testing by a single reference laboratory using OncoScanTM CNV Plus and targeted neuro-oncology NGS panels (2017-2021). Median age a t surgery was 51 years (range 34-74).
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Cinthya Zepeda Mendoza, Thomas Kollmeyer, Corinne Praska, Katherine Geiersbach, William Sukov, Patricia Greipp, Aditya Raghunathan, Caterina Giannini, Robert Jenkins, Cristiane Ida Source Type: research
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