Researches of calcium-activated chloride channel ANO1 intervening amyotrophic lateral sclerosis progression by activating EGFR and CaMKII signaling

CONCLUSIONS: Our results suggest that ANO1 plays an important role in the survival of ALS motor neurons. ANO1 can increase cell activity and reduce apoptosis by activating EGFR and CaMKII signals.PMID:37858681 | DOI:10.1016/j.brainresbull.2023.110792

Source: Brain Research Bulletin - October 20, 2023 Category: Neurology Authors: Ying Wang Weiwei Liang Tianhang Wang Chunting Zhang Yueqing Yang Chaohua Cong Xudong Wang Shuyu Wang Di Wang Di Huo Hongyong Wang Xiaoli Su Xingli Tan Honglin Feng Source Type: research