13q32.1 as a candidate region for physiological anisocoria

Conclusion The very specific region associated with anisocoria is one where microdeletions (or microduplications) are known to lead to abnormal development of pupil dilator muscle and hence to the autosomal dominant condition of microcoria. It is possible that alterations at 13q32.1 act by altering the expression of SOX21, which encodes a nuclear transcription factor.
Source: British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original articles - Laboratory science Source Type: research