Clinicopathologic characterization of cutaneous adult T-cell leukemia/lymphoma: A single tertiary care center experience in the United States

CONCLUSIONS: Pleomorphic large, atypical cells with CD4+/CD25+/CD7- immunophenotype from a non-"bathing trunk" location, especially in a patient from endemic regions, raise suspicion for ATLL. T-cell receptor gene rearrangement is almost always positive, and the neoplasm usually demonstrates multiple mutations by next-generation sequencing study.PMID:37830309 | DOI:10.1093/ajcp/aqad120

Source: American Journal of Clinical Pathology - October 13, 2023 Category: Pathology Authors: Mitul B Modi Alexandra Kiszluk Jiani N Chai Ukuemi Edema Maxwell Y Ma R Alejandro Sica Yanhua Wang Yang Shi Source Type: research