Anticonvulsant effects of isopimpinellin and its interactions with classic antiseizure medications and borneol in the mouse tonic-clonic seizure model: an isobolographic transformation

CONCLUSIONS: The most intriguing interaction was that for ISOP + VPA, for which the addition of BOR evoked a transition from antagonism to synergy in the mouse MES model.PMID:37821793 | DOI:10.1007/s43440-023-00532-x

Source: Pharmacological Reports - October 11, 2023 Category: Drugs & Pharmacology Authors: Jarogniew J Łuszczki Hubert Bojar Katarzyna Jankiewicz Magdalena Florek- Łuszczki Jaros ław Chmielewski Krystyna Skalicka-Wo źniak Source Type: research