Cardiac glycoside ouabain efficiently targets leukemic stem cell apoptotic machinery independent of cell differentiation status

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by an accumulation of immature leukemic myeloblasts initiating from leukemic stem cells (LSCs) —the subpopulation that is also ...

Source: Cell Communication and Signaling - October 12, 2023 Category: Molecular Biology Authors: Jirarat Poohadsuan, George A. O ’Doherty, Weerapat Owattanapanich, Smith Kungwankiattichai, Yon Rojanasakul, Surapol Issaragrisil and Sudjit Luanpitpong Tags: Research Source Type: research