Renal tumours of childhood: what's new in classification, morphology, molecular findings and prognosis

Despite being one of the most frequent solid tumours in children, renal tumours are uncommon. Their accurate diagnosis and staging are essential for the appropriate treatment because they comprise a variety of entities with a broad spectrum of clinical, histological, molecular biology, and prognostic features. Wilms tumour (WT) accounts for 80 –85% of renal tumours of childhood, whereas other tumours including mesoblastic nephroma, clear cell sarcoma, rhabdoid tumour, renal cell carcinoma, and others are extremely uncommon (up to 2%–4% each), which explains why they pose a significant diagnostic challenge for pathologists.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Mini-symposium: paediatric and perinatal pathology Source Type: research