Asymptomatic CMV infection at birth following maternal infection, valacyclovir treatment, and a subsequent negative amniocentesis. Case report

Recent evidence suggested that valacyclovir is currently the only pharmacological intervention able to reduce the risk of vertical CMV congenital infection in case of primary infection during pregnancy.So far, no data are available on the prognosis of children with congenital CMV infection diagnosed at birth after a negative amniocentesis whose mother were treated with valacyclovir during pregnancy, therefore it is essential to carry out a rigorous neurocognitive follow-up in these children in order to investigate the potential clinical consequence.

https://www.ejog.org/article/S0301-2115(23)00755-8/fulltext?rss=yes

Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - October 6, 2023 Category: OBGYN Authors: Maria Stefania Toti, Lorenzo Zammarchi, Lucia Pasquini, Irene Campolmi, Giulia Modi, Beatrice Borchi, Alessandro Bartoloni, Michele Trotta, Luisa Galli, Roberto Bernardini Tags: Full length article Source Type: research