The MEK-ERK-Egr-1 axis and its regulation in cardiovascular disease

This article reviews recent progress on the MEK-ERK-Egr-1 cascade, notably regulation in conjunction with factors and agents such as TET2, TRIB2, MIAT, SphK1, cAMP, teneligliptin, cholinergic drugs, red wine and flavonoids, wogonin, febuxostat, docosahexaenoic acid and AT1R blockade. Such insights should provide new opportunity for therapeutic intervention in CVD.PMID:37734428 | DOI:10.1016/j.vph.2023.107232
Source: Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research