Metformin Ameliorates Postoperative Cognitive Dysfunction through Regulation of the AMPK/SIRT1 Pathway

CONCLUSIONS: Through the AMPK/SIRT1 pathway, metformin can boost autophagy and reduce oxidative stress in cortical microglia in older rats, in turn improving postoperative cognitive function.PMID:37735113 | DOI:10.31083/j.jin2205110

Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Peiyu Jia Ji Che Junfeng Zhang Haibing Li Quanhong Zhou Yong Guo Source Type: research