Feasibility of delivering supervised exercise training following surgical resection and during adjuvant chemotherapy for pancreatic ductal adenocarcinoma (PRECISE): a case series

DiscussionThis case series provides preliminary evidence that concurrent exercise training during adjuvant therapy is safe, feasible and well tolerated, preventing an expected decline in functional fitness, muscular strength and health-related quality of life (HRQoL). Given the adverse effects of treatment, these findings are promising and provide further evidence for the inclusion of exercise training as a standard of care for surgical rehabilitation and managing treatment-related toxicities. Future research should explore the impact of exercise training during neoadjuvant chemotherapy, with prehabilitation now standard practice for borderline resectable disease.Trial registrationClinicalTrials.gov Identifier: NCT04305067, prospectively registered 12/03/2020,https://classic.clinicaltrials.gov/ct2/show/NCT04305067.
Source: BMC Sports Science, Medicine and Rehabilitation - Category: Sports Medicine Source Type: research