Challenges to delivering evidence-based management for long COVID

Early on in the COVID-19 pandemic, scientists forewarned of a potential medium to long-term post-acute sequelae in patients infected with SARS-CoV-2, similar to that documented in bacterial,1 protozoan and viral infections including Epstein-Barr virus,2 Ebola virus,3 dengue virus,4 Chikunguña virus,5 going far back to the influenza pandemic in 1918.6 These varied symptoms following acute SARS-CoV-2 infection is now termed as long COVID and is also known as long-haulers syndrome, post COVID-19 condition (PCC),7 ‘post-acute sequelae of SARS-CoV-2 infection (PASC)’,7 ‘chronic COVID’ and many other terms. The Department of Health and Human Services in collaboration with the US Centers for Disease Control and Prevention broadly defines long COVID as ‘signs, symptoms, and conditions that continue or develop after initial COVID-19 infection’.8 Through a global consensus, the WHO, in October 2021, defined post...
Source: Evidence-Based Medicine - Category: Internal Medicine Authors: Tags: Open access, COVID-19 Analysis Source Type: research