Role of S100 and YKL40 on Intraventricular Cerebral Hemorrhages in the Preterm Infant and the Neuroprotective Role of miR-138-siRNAs-HIF-1a and miR-21-siRNAs-HVCN1 in Neonatal Mice with Nerve Injury

CONCLUSION: Our findings demonstrate that miR-138-siRNAs-HIF-1a and miR-21-siRNAs-HVCN1 injections prevent cerebral ischemia-induced brain damage in hypoxia mice by increasing HVCN1 and HIF-1a and decreasing S100b, which in turn lessens apoptosis and epilepsy in hypoxic mice.PMID:37724672 | DOI:10.2174/0929867331666230915103147

Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Roghayeh Ijabi Zachary A Kaminsky Parisa Roozehdar Janat Ijabi Hemen Moradi-Sardareh King Hwa Ling Najmeh Tehranian Source Type: research