Association between HLA alleles and beta-lactam antibiotics-related severe cutaneous adverse reactions

Conclusion: This study demonstrated the candidate HLA alleles that are significantly associated with several phenotypes of beta-lactam antibiotics-related SCARs. However, whether the HLA alleles observed in this study can be used as valid genetic markers for SCARs related to beta-lactam antibiotics needs to be further explored in other ethnicities and larger cohort studies.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research