Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus

CONCLUSION: Our findings highlight a previously unknown cohesive picture of the glutamatergic implications of LiCl action that persist long after the end of its administration, revealing for the first time a profound and persistent reorganization of the glutamatergic postsynaptic density receptor composition and structure.PMID:37711124 | DOI:10.2174/1570159X21666230913144420

https://pubmed.ncbi.nlm.nih.gov/37711124/?utm_source=no_user_agent&utm_medium=rs...

Source: Current Neuropharmacology - September 15, 2023 Category: Drugs & Pharmacology Authors: Lucia Caffino Giorgia Targa Anne Stephanie Mallien Francesca Mottarlini Beatrice Rizzi Judith R Homberg Peter Gass Fabio Fumagalli Source Type: research