The Evolution of Epilepsy Surgery in Tuberous Sclerosis in Sweden: a national registry study

Tuberous sclerosis complex (TSC) is a rare genetic disorder caused by pathogenic heterozygous variants in the mechanistic target of rapamycin (mTOR) pathway regulators, TSC1 or TSC2 [1]. Disinhibition of mTOR leads to the growth of benign hamartomas in several organs. Epilepsy is the most prevalent neurological manifestation in patients with TSC, occurring in approximately 90% of patients and 80%
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research