Narrative review: respiratory tract microbiome and never smoking lung cancer

CONCLUSIONS: These findings suggest potential carcinogenic processes such as increased inflammation associated with changes in flora. Additionally, studies showed that increase in certain taxa such as Bacteroides and Spirochetes might have a protective effect on lung cancer risk. The review also provides insight into how understanding the microbial changes can be beneficial for lung cancer treatment and disease-free survival. Larger studies in different populations need to be performed to strengthen the current associations between microbial diversity and lung cancer risk.PMID:37691669 | PMC:PMC10482636 | DOI:10.21037/jtd-22-885
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Authors: Source Type: research