Activation of the DNA damage response pathway in the infected gastric tissue with Helicobacter pylori: a case-control study

CONCLUSIONS: Our results provide new data that may support the potential involvement of H. pylori infection in the activation of genes involved in DNA damage response, mainly through a non-homologous end-joining DNA repair system that might be linked to mutagenesis in the pre-cancerous gastric tissue.PMID:37699095 | DOI:10.3855/jidc.17655

Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Amiratabak Rajaei Armin Ghameshlou Reza Shirkoohi Abbas Shakoori Farahani Seyedeh Zohre Mirbagheri Ronak Bakhtiari Melika Sadat Haeri Ali Rashidi-Nezhad Masoud Alebouyeh Source Type: research