Transcriptional analysis of Helicobacter pylori cytotoxic-associated gene-pathogenicity island  in response to different pH levels and proton pump inhibitor exposure

ConclusionOur results showed that omeprazole could increase the expression ofH. pylori cagA andcagL at acidic pH. Heterogeneity among the strains probably has an impact on the extent of their interplay with PPIs. Further studies are needed to establish this correlation.Graphical Abstract
Source: Indian Journal of Gastroenterology - Category: Gastroenterology Source Type: research