T Cell Exhaustion and Activation Markers in Pancreatic Cancer: A Systematic Review

ConclusionSince the exhaustion markers are upregulated in patients, single or multiple markers can be targeted in immunotherapies. Knowledge of the dynamics of these markers at various cancer stages will help in determining the right immunotherapy for pancreatic cancer patients. Stage-wise comparison could also be made possible by developing in vitro models.
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research