Overexpression of CD2/CD27 could inhibit the activation of nitrogen metabolism pathways and suppress M2 polarization of macrophages, thereby preventing brain metastasis of breast cancer

CONCLUSION: In the tumor microenvironment, overexpression of CD2/CD27 inhibited the activation of nitrogen metabolism pathways and suppressed M2 polarization of macrophages, thereby preventing brain metastasis of breast cancer.PMID:37666207 | DOI:10.1016/j.tranon.2023.101768

Source: Translational Oncology - September 4, 2023 Category: Cancer & Oncology Authors: Guanyou Huang Yujuan Wu Hongchuan Gan Liangzhao Chu Source Type: research