The impact of pretransplant suspected HLA antibody on the long-term outcome of the graft kidney: A retrospective cohort study

CONCLUSION: KTRs with suspected HLA antibodies before kidney transplantation have worse graft function than the preoperative HLA antibody-negative recipients in the long-term posttransplant follow-up. The specific load capacity of HLA mismatches, the age of the recipient and the urinary protein was found to be negatively correlated with long-term posttransplant renal outcomes. It is necessary to undergo further HLA specificity analysis for recipients with suspected HLA antibodies in HLA antibody screen test to explicit HLA mismatches and improve long-term posttransplant outcomes.PMID:37657691 | DOI:10.1016/j.trim.2023.101922
Source: Transplant Immunology - Category: Transplant Surgery Authors: Source Type: research