Mechanistic insights from high resolution DNA damage analysis to understand mixed radiation exposure

In conclusion, early differences in response to complex DNA damage may lead to a stronger cell kill induced by fractionated exposure, which suggest a therapeutic potential of combined high and low LET irradiation.PMID:37595330 | DOI:10.1016/j.dnarep.2023.103554

Source: DNA Repair - August 18, 2023 Category: Genetics & Stem Cells Authors: Pamela Akuwudike Milagrosa L ópez-Riego J ózef Ginter Lei Cheng Anna Wieczorek Katarzyna Życieńska Ma łgorzata Łysek-Gładysińska Andrzej Wojcik Beata Brzozowska Lovisa Lundholm Source Type: research