Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease

A significant proportion of patients with peripheral artery disease (PAD) displays a poor response to aspirin and/or the platelet P2Y12 receptor antagonist clopidogrel. This phenomenon is reflected by high on-treatment platelet reactivity (HTPR) in platelet function assays in vitro and is associated with an increased risk of adverse cardiovascular events.

Source: Thrombosis Research - September 1, 2023 Category: Hematology Authors: G. Baidildinova, A. Pallares Robles, V. ten Cate, B.M.M. Kremers, S. Heitmeier, H. ten Cate, B.M.E. Mees, H.M.H. Spronk, P.S. Wild, A.J. ten Cate-Hoek, K. Jurk Source Type: research