Cancers, Vol. 15, Pages 4361: The Impact of Sidedness on the Efficacy of Anti-EGFR-Based First-Line Chemotherapy in Advanced Colorectal Cancer Patients in Real-Life Setting & mdash;A Nation-Wide Retrospective Analysis (RACER)
Cancers, Vol. 15, Pages 4361: The Impact of Sidedness on the Efficacy of Anti-EGFR-Based First-Line Chemotherapy in Advanced Colorectal Cancer Patients in Real-Life Setting—A Nation-Wide Retrospective Analysis (RACER)
Cancers doi: 10.3390/cancers15174361
Authors:
Paweł Michał Potocki
Rafał Wiśniowski
Dominik Haus
Zbyszko Chowaniec
Maciej Kozaczka
Magdalena Kustra
Marzenna Samborska-Plewicka
Marcin Szweda
Danuta Starzyczny-Słota
Magdalena Michalik
Grzegorz Słomian
Aneta Lebiedzińska
Natalia Jonak-Olczyk
Natalia Łaszewska-Kraińska
Krzysztof Adamowicz
Piotr Kolenda
Anna Drosik-Kwaśniewska
Marek Szwiec
Robert Dziura
Justyna Czech
Maria Dąbrowska
Ewa Nowakowska-Zajdel
Ewa Klank-Sokołowska
Kamil Konopka
Łukasz Kwinta
Jolanta Dobrzańska
Piotr J. Wysocki
Anti-EGFR antibodies combined with chemotherapy doublets are a cornerstone of the upfront treatment of colorectal cancer. RAS and BRAF mutations are established negative predictive factors for such therapy. The primary tumour located in the proximal colon has recently emerged as another negative predictive factor. We have conducted a retrospective multicentre study to collect data on real-world population characteristics, practice patterns, and outcomes in patients with metastatic colorectal cancer treated in a first-line setting with either cetuximab or panitumumab in combination with either FOLFOX or FOLFIRI chemotherapy. The presented analysis focu...
Source: Cancers - Category: Cancer & Oncology Authors: Pawe ł Michał Potocki Rafa ł Wiśniowski Dominik Haus Zbyszko Chowaniec Maciej Kozaczka Magdalena Kustra Marzenna Samborska-Plewicka Marcin Szweda Danuta Starzyczny-S łota Magdalena Michalik Grzegorz S łomian Aneta Lebiedzi ńska Natalia Jonak-Olczyk Tags: Article Source Type: research
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