EZH2-regulated PARP 1 Expression is a Likely Mechanism for the Chemoresistance of Gliomas to Temozolomide

CONCLUSION: EZH2 PARP 1 signaling axis is possibly responsible for the chemoresistance of gliomas to TMZ. Simultaneously inhibiting these two genes may improve the outcome of TMZ chemotherapy.PMID:37594167 | DOI:10.2174/1568009623666230818151830

Source: Current Cancer Drug Targets - August 18, 2023 Category: Cancer & Oncology Authors: Qiang Liang Bing Wang Chenran Zhang Chaoli Song Junyu Wang Wei Sun Lei Jiang Jing Lin Source Type: research