Metabolic signature of 13C-labeled wheat bran consumption related to gut fermentation in humans: a pilot study

ConclusionThis pilot study allowed to consider novel procedures for the development of biomarkers revealing dietary fiber-gut microbiota interactions. The non-invasive assessment of exhaled gas following13C-labeled fibers ingestion enabled to decipher distinct fermentation profiles: high-CH4 producers vs low-CH4 producers. The isotope labeling permits a specific in vivo characterisation of the dietary fiber impact consumption on microbiota metabolite production.Clinical trial registrationThe study has been registered under the number NCT03717311 at ClinicalTrials.gov on October 24, 2018.
Source: European Journal of Nutrition - Category: Nutrition Source Type: research