A well-differentiated neuroendocrine tumour of high grade

Neuroendocrine neoplasms (NEN) are a group of epithelial neoplasms with neural and endocrine differentiation, one of the main sites of origin being the gastrointestinal tract and pancreas (GEP). One of the common groups of GEP-NEN, well-differentiated neuroendocrine tumour (WD-NET), is a biologically distinct group from poorly differentiated neuroendocrine carcinoma (PD-NEC). Accurate histopathological distinction of WD-NET from PD-NEC is critical for prognostication and deciding on optimal therapeutic approaches.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Short case Source Type: research