Apelin inhibits the proliferation and migration of rat PASMCs via the activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia.

This study provides the evidence that exogenous apelin treatment contributes to inhibit the proliferation and migration of PASMCs by regulating the level of autophagy.
PMID: 24447518 [PubMed - as supplied by publisher]

Source: J Cell Mol Med - January 22, 2014 Category: Molecular Biology Authors: Zhang H, Gong Y, Wang Z, Jiang L, Chen R, Fan X, Zhu H, Han L, Li X, Xiao J, Kong X Tags: J Cell Mol Med Source Type: research