Establishing minimally important differences for cardiac MRI end-points in pulmonary arterial hypertension

Conclusions This study establishes clinically relevant CMR MIDs for how a patient "feels, functions or survives" in response to PAH treatment. These findings provide further support for the use of CMR as a clinically relevant clinical outcome measure and will aid trial size calculations for studies using CMR.

http://erj.ersjournals.com/cgi/content/short/62/2/2202225?rss=1

Source: European Respiratory Journal - August 3, 2023 Category: Respiratory Medicine Authors: Alabed, S., Garg, P., Alandejani, F., Dwivedi, K., Maiter, A., Karunasaagarar, K., Rajaram, S., Hill, C., Thomas, S., Gossling, R., Sharkey, M. J., Salehi, M., Wild, J. M., Watson, L., Hameed, A., Charalampopoulos, A., Lu, H., Rothman, A. M. K., Thompson, Tags: Pulmonary vascular disease Original Articles: Pulmonary vascular disease Source Type: research