O-062 Novel endovascular technique for pharmacological block of superior cervical ganglion prevents sympathetic mediated cerebral vasospasm

ConclusionsWe demonstrate a novel endovascular technique of transmural delivery of lidocaine to the SCG and carotid artery perivascular tissues to inhibit sympathetic mediated cerebral vasospasm. These results suggest promising translation to humans for clinical use in patients suffering from cerebral vasospasm.Abstract O-062 Figure 1AP view of right neck showing positioning and transmural lidocaine injection using the Micro-Infusion Device. (A) Fluoroscopy single shot showing Micro-Infusion Device positioned in the right common carotid artery with needle aimed towards the SCG. Electric needle stimulators placed in the right SCG (black arrow). Distal and proximal radio-opaque indicators of the Micro-Infusion Device (black arrowheads). Orientation marker for Micro-Infusion Device needle (white arrowhead). (B) Fluoroscopy single shot image showing immediate post injection of 1% lidocaine in 50% contrast solution (2cc)Disclosures W. Kim: 1; C; NIH Research Education Programs (R25). H. Samarage: None. M. Jaffari: None. D. Zarrin: None. K. Goel: None. X. Qi: None. A. Wang: None. J. Johnson: None. G. Colby: 1; C; Casa Colina Foundation research grant.
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: SNIS 20th annual meeting oral abstracts Source Type: research