O-058 PPODA as a mechanically stable and biocompatible coating for endovascular stents and flow diverters

ConclusionPPODA polymer coatings can improve biocompatibility and prevent thrombosis on FDs and stents by pre-coating wires for braiding or post-coating laser-cut stent devices. Future work will compare coating integrity and biocompatibility to established devices (i.e Pipeline Shield® and Fred-X®). Materials like PPODA may provide FDs and stents with a mechanically stable scaffold coating that promotes continuous re-endothelialization over an aneurysm neck, which can eliminate thrombosis and reduce recanalization rates.Abstract O-058 Figure 1SH-PEG-Silane and PPODA bound to a nitinol wire surface. Figure la is an SEM image of a nitinol wire with these polymers attached and Figure 1b is a graphic depiction of this attachmentDisclosures S. Robertson: 5; C; Northern Arizona University. W. Merritt: 1; C; SNIS Young Investigator Research Grant. 4; C; Aneuvas Technologies, Inc. 5; C; Aneuvas Technologies, Inc. T. Becker: 1; C; SNIS Young Investigator Research Grant. 2; C; United Biologics. 4; C; Aneuvas Technologies, Inc. 5; C; Northern Arizona University. A. Ducruet: 2; C; Medtronic, Penumbra, Oculus, Stryker, Balt, Koswire. 4; C; Aneuvas Technologies, Inc. 5; C; Barrow Neurological Institute.
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: SNIS 20th annual meeting oral abstracts Source Type: research