O-041 Primary results of the pRESET for occlusive stroke treatment (PROST) randomized clinical trial

Conclusions and RelevancePROST is the first randomized clinical trial aiming to compare a novel versus an established stent-retriever technology, establishing a new scientific benchmark for stroke device trials. In all primary & secondary endpoints and analysis, the pre-specified threshold of non-inferiority was met.(ClinicalTrials.gov: NCT03994822)Disclosures R. Hanel: 1; C; NIH, Interline Endowment, Microvention, Stryker, CNX, Balt. 2; C; Medtronic, Stryker, Cerenovus, Microvention, Phenox, Rapid Medical, Q’Apel. 4; C; InNeuroCo, Cerebrotech, eLum, Endostream, Three Rivers Medical Inc, Scientia, RisT, BlinkTBI, Corindus. J. Klisch: None. M. Möhlenbruch: None. D. Vollherbst: None. C. Ulfert: None. H. Bozorgchami: None. E. A. Samaniego: None. D. S. Liebeskind: None. D. Lobsien: None. D. Pielenz: None. E. Sauvageau: None. A. Aghaebrahim: None. W. M. Clark: None. R. Priest: None. S. Ortega-Gutierrez: None. D. Lopes: None. J. Billingsley: None. D. C. Haussen: None. A. R. Al-Bayati: None. A. H. Siddiqui: None. M. Chen: None. P. Schramm: None. S. Narayanan: None. C. Roth: None. T. Boeckh-Behrens: None. A. E. Hassan: None. J. T. Fifi: None. R. Budzik: None. J. W. Tarpley: None. R. Starke: None. E. Raz: None. R. Nogueira: None.

Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Hanel, R., Klisch, J., Möhlenbruch, M., Vollherbst, D., Ulfert, C., Bozorgchami, H., Samaniego, E., Liebeskind, D., Lobsien, D., Pielenz, D., Sauvageau, E., Aghaebrahim, A., Clark, W., Priest, R., Ortega-Gutierrez, S., Lopes, D., Billingsley, J., Tags: SNIS 20th annual meeting oral abstracts Source Type: research