Medications for specific phenotypes of heart failure with preserved ejection fraction classified by a machine learning-based clustering model

Conclusions
Machine learning-based clustering may have the potential to identify populations in which specific medications may be effective. This study suggests the effectiveness of MRA, ACEi or ARB and statin for specific phenotypes of HFpEF.

Trial registration number
UMIN000021831.

Source: Heart - July 27, 2023 Category: Cardiology Authors: Sotomi, Y., Hikoso, S., Nakatani, D., Okada, K., Dohi, T., Sunaga, A., Kida, H., Sato, T., Matsuoka, Y., Kitamura, T., Komukai, S., Seo, M., Yano, M., Hayashi, T., Nakagawa, A., Nakagawa, Y., Tamaki, S., Ohtani, T., Yasumura, Y., Yamada, T., Sakata, Y., o Tags: Open access Heart failure and cardiomyopathies Source Type: research