Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia

CONCLUSIONS: Our in-silico comparative analysis between the VDAC1 gene and its VDAC1P8 pseudogene, together with experimental data produced in AML cellular models, indicate a specific over-expression of the VDAC1P8 pseudogene in AML, correlated with a downregulation of the parental VDAC1 gene.PMID:37344914 | PMC:PMC10286422 | DOI:10.1186/s40659-023-00446-1

Source: In Silico Biol - June 21, 2023 Category: Biology Authors: Xena Giada Pappalardo Pierpaolo Risiglione Federica Zinghirino Angela Ostuni Daniela Luciano Faustino Bisaccia Vito De Pinto Francesca Guarino Angela Messina Source Type: research