Effect of siRNA-mediated silencing of p53R2 gene on sensitivity of T-ALL cellsto Daunorubicin

CONCLUSION: The results of the present study showed that silencing of p53R2 using siRNA can significantly increase the antitumor effects of Daunorubicin on T-ALL cells. Therefore, p53R2 siRNA has the potential to be used as an adjuvant therapy in combination with Daunorubicin in T-ALL.PMID:37419428 | DOI:10.1016/j.gene.2023.147622

Source: Gene - July 7, 2023 Category: Genetics & Stem Cells Authors: Omid KianiGhalesardi Farhad Zaker Abbas Ghotaslou Hassan Boustani Mohammad Reza Rezvani Jafar Kiani Minoo Shahidi Source Type: research