High interindividual variability in LDL-cholesterol reductions after inclisiran administration in a real-world multicenter setting in Germany

CONCLUSION: In this real-world patient population referred to German lipid clinics for elevated LDL-C levels, inclisiran demonstrated a high interindividual variability in LDL-C reductions. Further research is warranted to elucidate reasons for the interindividual variability in drug efficacy.PMID:37422840 | DOI:10.1007/s00392-023-02247-8

Source: Clin Med Res - July 9, 2023 Category: Research Authors: U Makhmudova U Schatz N Perakakis U Kassner F Schumann C Axthelm P St ürzebecher D L Sinning A Doevelaar B Rohn T Westhoff A Vogt M Scholl U K ästner J-A Geiling K Stach J Mensch E Lorenz C Paitazoglou I Eitel A Baessler E Steinhagen-Thiessen W Koenig P Source Type: research