Dysregulated Rbfox2 produces aberrant splicing of CaV1.2 calcium channel in diabetes-induced cardiac hypertrophy

L-type Ca2+ channel CaV1.2 is essential for cardiomyocyte excitation, contraction and gene transcription in the heart, and abnormal functions of cardiac CaV1.2 channels are presented in diabetic cardiomyopathy. H...

Source: Cardiovascular Diabetology - July 6, 2023 Category: Cardiology Authors: Pengpeng Li, Dongxia Qin, Tiange Chen, Wei Hou, Xinyu Song, Shumin Yin, Miaomiao Song, W.C. Hewith A. Fernando, Xiaojie Chen, Yu Sun and Juejin Wang Tags: Research Source Type: research