Generation and measurement of low-temperature plasma for cancer therapy: a historical review

Free Radic Res. 2023 Jul 4:1-32. doi: 10.1080/10715762.2023.2230351. Online ahead of print.ABSTRACTThis review provides a description of the historical background of the development of biological applications of low-temperature plasmas. The generation of plasma, methods and devices, plasma sources, and measurements of plasma properties, such as electron dynamics and chemical species generation in both gaseous and aqueous phases, were assessed. Currently, direct irradiation methods for plasma discharges contacting biological surfaces, such as the skin and teeth, are related to plasma biological interactions. Indirect methods using plasma-treated liquids are based on plasma-liquid interactions. The use of these two methods is rapidly increasing in preclinical studies and cancer therapy. The authors address the prospects for further developments in cancer therapeutic applications by understanding the interactions between the plasma and living organisms.PMID:37395063 | DOI:10.1080/10715762.2023.2230351

Source: Free Radical Research - July 3, 2023 Category: Research Authors: Kenji Ishikawa Keigo Takeda Shinji Yoshimura Takashi Kondo Hiromasa Tanaka Shinya Toyokuni Kae Nakamura Hiroaki Kajiyama Masaaki Mizuno Masaru Hori Source Type: research